Cat Dissection Structures Essay

Healthy kidneys make hormones such as renin and angiotensin. These hormones regulate how much sodium (salt) and fluid the body keeps, and how well the blood vessels can expand and contract. This, in turn, helps control blood pressure. They do this by regulating: †¢ The amount of water in the body. If there is too much water in the body (fluid overload) blood pressure will go up. If there is too little water in the body (dehydration) the blood pressure will drop. †¢ The width of the arteries. The arteries constantly change in width as blood flows through them. The narrower the arteries, the higher the blood pressure. Renin helps control narrowing of the arteries. Failing kidneys often make too much renin. This raises blood pressure. If your blood pressure is high, your heart is working harder than normal to pump blood through your body. High blood pressure (also called hypertension) caused by a breakdown in these functions is common in people with kidney failure. It is also a complication, a secondary condition caused by kidney failure. †¢ RBC production? o The urinary system controls red blood cell production by secreting the hormone erythropoietin. . What structures enter or exit at the hilum of the kidney? †¢ Ureters, renal blood vessels, lymphatics, and nerves enter and exit at the hilum Know the anatomy of the kidney so that you could recognize the following parts from a description or on a diagram: capsule, hilum, renal artery, renal vein, ureter, cortex, medulla, papillae, renal columns, minor and major calyces, renal pelvis. The Kidney is bean-shaped and located in the lumbar region of the body. The kidney is described as being Retroperitoneal-that is, it is located between the dorsal body wall nd the parietal peritoneum. 1. An average human kidney weighs about 5 ounces. 2. Sitting on top of each kidney is a single adrenal gland that essentially has no influence on the kidney. B. The Renal Hilum-vertical cleft on the medial surface of the kidney, that leads into an internal space within the kidney known as the Renal Sinus. 1. The ureter, the renal blood vessels, lymphatics and nerves all join each other at the hilum and occupy the renal sinus. C. There are Three Layers of Support Tissue Surrounding each kidney. The layers are: 1. The Fibrous Capsule-a capsule-like layer that prevents infections in surrounding regions from spreading to the kidney. 2. The Perirenal Fat Capsule-a thick layer of adipose tissue that attaches the kidney to the posterior body wall and cushions it against blows. 3. The Renal Fascia-an outer layer of fibrous connective tissue that anchors the kidney and adrenal glands to surrounding tissues.   Three Distinct Internal Segments in the Human Kidney: 1. The Renal Cortex-light colored, superficial region of the kidney. This area has a granular appearance. . The Renal Medulla-a dark red or brown colored region in the kidney. The medulla contains cone-shaped areas known as the Medullary or Renal Pyramids. a. The base of each pyramid faces towards the cortex and the apex (Papilla) points internally. b. The pyramids contain bundles of microscopic urine-collecting tubules and capillaries. Structures known as the Renal Columns separate the pyramids from each other. c. Each pyramid and its surr ounding tissue makes up one of eight lobes of a kidney. 3. The Renal Pelvis-a funnel-shaped tube that is continuous with the ureter leaving he hilum. a. Branching extensions of the Pelvis form two or three Major Calyces, each of which subdivides to form several Minor Calyces. b. The Minor Calyces are cup-shaped areas that enclose the papillae of the pyramids. 1) The calyces collect urine, which drains from the papillae, and empty into the renal pelvis. The urine then flows through the renal pelvis and into the ureter which moves it to the bladder where it is stored. 2) Smooth muscle lines the walls of the calyces, the pelvis and the ureter. Urine is pushed through these areas via peristalsis. In what part of the kidney are most of the nephrons located? Renal Cortex 4. Blood supply of the kidney: †¢ Branch of aorta that enters kidney is the renal artery, which divides several times as it moves toward the cortex. †¢ At the base of the renal pyramids, the arcuate arteries branch into interlobular arteries that branch into afferent arterioles that deliver blood to the glomerulus. †¢ The efferent arterioles exit the glomerulus and give rise to the peritubular and vasa recta capillaries surrounding the renal tubule. Secretion and reabsorption occurs between the tubule and bloodstream in these capillaries.

Foundation’s Edge CHAPTER THREE HISTORIAN

HISTORIAN Janov Pelorat was white-haired and his face, in repose, looked rather empty. It was rarefy in anything but repose. He was of average height and weight and tended to move without haste and to speak with deliberation. He seemed considerably older than his fifty-two years. He had never left Terminus, something that was most unusual, especially for one of his profession. He himself wasn't sure whether his sedentary ways were because of – or in spite of – his obsession with history. The obsession had come upon him quite suddenly at the age of fifteen when, during some indisposition, he was given a book of early legends. In it, he found the repeated motif of a world that was alone and isolated – a world that was not even aware of its isolation, since it had never known anything else. His indisposition began to clear up at once. Within two days, he had read the book three times and was out of bed. The day after that he was at his computer terminal, checking for any records that the Terminus University Library might have on similar legends. It was precisely such legends that had occupied him ever since. The Terminus University Library had by no means been a great resource in this respect but, when he grew older, he discovered the joys of interlibrary loans. He had printouts in his possession which had been taken off hyper-radiational signals from as far away as Ifnia. He had become a professor of ancient history and was now beginning his first sabbatical – one for which he had applied with the idea of taking a trip through space (his first) to Trantor itself – thirty-seven years later. Pelorat was quite aware that it was most unusual for a person of Terminus to have never been in space. It had never been his intention to be notable in this particular way. It was just that whenever he might have gone into space, some new book, some new study, some new analysis came his way. He would delay his projected trip until he had wrung the new matter dry and had added, if possible, one more item of fact, or speculation, or imagination to the mountain he had collected. In the end, his only regret was that the particular trip to Trantor had never been made. Trantor had been the capital of the First Galactic Empire. It had been the seat of Emperors for twelve thousand years and, before that, the capital of one of the most important pre-Imperial kingdoms, which had, little by little, captured or otherwise absorbed the other kingdoms to establish the Empire. Trantor had been a world-girdling city, a metal-coated city. Pelorat had read of it in the works of Gaal Dornick, who had visited it in the time of Hari Seldon himself. Dornick's volume no longer circulated and the one Pelorat owned might have been sold for half the historian's annual salary. A suggestion that he might part with it would have horrified the historian. Of course, what Pelorat cared about, as far as Trantor was concerned, was the Galactic Library, which in Imperial times (when it was the Imperial Library) had been the largest in the Galaxy. Trantor was the capital of the largest and most populous Empire humanity had ever seen. It had been a single worldwide city with a population well in excess of forty billion, and its Library had been the gathered record of all the creative (and not-so-creative) work of humanity, the full summary of its knowledge. And it was all computerized in so complex a manner that it took experts to handle the computers. What was more, the Library had survived. To Pelorat, that was the amazing thing about it. When Trantor had fallen and been sacked, nearly two and a half centuries before, it had undergone appalling destruction, and the tales of human misery and death would not bear repeating – yet the Library had survived, protected (it was said) by the University students, who used ingeniously devised weapons. (Some thought the defense by the students might well have been thoroughly romanticized.) In any case, the Library had endured through the period of devastation. Ebling Mis had done his work in an intact Library in a ruined world when he had almost located the Second Foundation (according to the story which the people of the Foundation still believed, but which historians have always treated with reserve). The three generations of Darells – Bayta, Toran, and Arkady – had each, at one time or another, been on Trantor. However, Arkady had not visited the Library, and since her time the Library had not impinged on Galactic history. No Foundationer had been on Trantor in a hundred and twenty years, but there was no reason to believe the Library was not still there. That it had made no impingement was the surest evidence in favor of its being there. Its destruction would surely have made a noise. The Library was outmoded and archaic – it had been so even in Ebling Mis's time – but that was all to the good. Pelorat always rubbed his hands with excitement when he thought of an old and outmoded Library. The older and the more outmoded, the more likely it was to have what he needed. In his dreams, he would enter the Library and ask in breathless alarm, â€Å"Has the Library been modemized? Have you thrown out the old tapes and computerizations?† And always he imagined the answer from dusty and ancient librarians, â€Å"As it has been, Professor, so is it still.† And now his dream would come true. The Mayor herself had assured him of that. How she had known of his work, he wasn't quite sure. He had not succeeded in publishing many papers. Little of what he had done was solid enough to be acceptable for publication and what had appeared had left no mark. Still, they said Branno the Bronze knew all that went on in Terminus and had eyes at the end of every finger and toe. Pelorat could almost believe it, but if she knew of his work, why on Terminus didn't she see its importance and give him a little financial support before this? Somehow, he thought, with as much bitterness as he could generate, the Foundation had its eyes fixed firmly on the future. It was the Second Empire and their destiny that absorbed them. They had no time, no desire, to peer back into the past – and they were irritated by those who did. The more fools they, of course, but he could not single-handedly wipe out folly. And it might be better so. He could hug the great pursuit to his own chest and the day would come when he would be remembered as the great Pioneer of the Important. That meant, of course (and he was too intellectually honest to refuse to perceive it), that he, too, was absorbed in the future – a future in which he would be recognized, and in which he would be a hero on a par with Hari Seldon. In fact, he would be the greater, for how could the working out of a clearly visualized future a millennium long stand comparison with the working out of a lost past at least twenty-five millennia old. And this was the day; this was the day. The Mayor had said it would be the day after Seldon's image made its appearance. That was the only reason Pelorat had been interested in the Seldon Crisis that for months had occupied every mind on Terminus and indeed almost every mind in the Federation. It had seemed to him to make the most trifling difference as to whether the capital of the Foundation had remained here at Terminus, or had been shifted somewhere else. And now that the crisis had been resolved, he remained unsure as to which side of the matter Hari Seldon had championed, or if the matter under dispute had been mentioned at all. It was enough that Seldon had appeared and that now this was the day. It was a little after two in the afternoon that a ground-car slid to a halt in the driveway of his somewhat isolated house just outside Terminus proper. A rear door slid back. A guard in the uniform of the Mayoralty Security Corps stepped out, then a young man, then two more guards. Pelorat was impressed despite himself. The Mayor not only knew of his work but clearly considered it of the highest importance. The person who was to be his companion was given an honor guard, and he had been promised a first-class vessel which his companion would be able to pilot. Most flattering! Most – Pelorat's housekeeper opened the door. The young man entered and the two guards positioned themselves on either side of the entrance. Through the window, Pelorat saw that the third guard remained outside and that a second ground-car had now pulled up. Additional guards! Confusing! He turned to find the young man in his room and was surprised to find that he recognized him. He had seen him on holocasts. He said, â€Å"You're that Councilman. You're Trevize!† â€Å"Golan Trevize. That's right. You are Professor Janov Pelorat?† â€Å"Yes, yes,† said Pelorat. â€Å"Are you he who will – â€Å" â€Å"We are going to be fellow travelers,† said Trevize woodenly. â€Å"Or so I have been told.† â€Å"But you're not a historian.† â€Å"No, I'm not. As you said, I'm a Councilman, a politician.† â€Å"Yes, Yes, But what am I thinking about? I am a historian, therefore what need for another? You can pilot a spaceship.† â€Å"Yes, I'm pretty good at that.† â€Å"Well, that's what we need, then. Excellent! I'm afraid I'm not one of your practical thinkers, young man, so if it should happen that you are, we'll make a good team.† Trevize said, â€Å"I am not, at the moment, overwhelmed with the excellence of my own thinking, but it seems we have no choice but to try to make it a good team.† â€Å"Let's hope, then, that I can overcome my uncertainty about space. I've never been in space, you know, Councilman. I am a groundhog, if that's the term. Would you like a glass of tea, by the way? I'll have Moda prepare us something. It is my understanding that it will be some hours before we leave, after all. I am prepared right now, however. I have what is necessary for both of us. The Mayor has been most co-operative. Astonishing – her interest in the project.† Trevize said, â€Å"You've known about this, then? How long?† â€Å"The Mayor approached me† (here Pelorat frowned slightly and seemed to be making certain calculations) â€Å"two, or maybe three, weeks ago. I was delighted. And now that I have got it clear in my head that I need a pilot and not a second historian, I am also delighted that my companion will be you, my dear fellow.† â€Å"Two, maybe three, weeks ago,† repeated Trevize, sounding a little dazed. â€Å"She was prepared all this time, then. And I†¦Ã¢â‚¬  He faded out. â€Å"Pardon me?† â€Å"Nothing, Professor. I have a bad habit of muttering to myself. It is something you will have to grow accustomed to, if our trip extends itself.† â€Å"It will. It will,† said Pelorat, bustling the other to the dining room table, where an elaborate tea was being; prepared by his housekeeper. â€Å"Quite open-ended. The Mayor said we were to take as long as we liked and that the Galaxy lay all before us and, indeed, that wherever we went we could call upon Foundation funds. She said, of course, that we would have to be reasonable. I promised that much.† He chuckled and rubbed his hands: â€Å"Sit down, my good fellow, sit down. This may be our last meal on Terminus for a very long time.† Trevize sat down. He said, â€Å"Do you have a family, Professor?† â€Å"I have a son. He's on the faculty at Santanni University. A chemist, I believe, or something like that. He took after his mother's side. She hasn't been with me for a long time, so you see I have no responsibilities, no active hostages to fortune. I trust you have none – help yourself to the sandwiches, my boy.† â€Å"No hostages at the moment. A few women. They come and go.† â€Å"Yes. Yes. Delightful when it works out. Even more delightful when you find it need not be taken seriously. – No children, I take it. â€Å"None.† â€Å"Good! You know, I'm in the most remarkable good humor. I was taken aback when you first came in. I admit it. But I find you quite exhilarating now. What I need is youth and enthusiasm and someone who can find his way about the Galaxy. We're on a search, you know. A remarkable search.† Pelorat's quiet face and quiet voice achieved an unusual animation without any particular change in either expression or intonation. â€Å"I wonder if you have been told about this. Trevize's eyes narrowed. â€Å"A remarkable search?† â€Å"Yes indeed. A pearl of great price is hidden among the tens of millions of inhabited worlds in the Galaxy and we have nothing but the faintest clues to guide us. just the same, it will be an incredible prize if we can find it. If you and I can carry it off, my boy – Trevize, I should say, for I don't mean to patronize – our names will ring down the ages to the end of time.† â€Å"The prize you speak of – this pearl of great price.† â€Å"I sound like Arkady Darell – the writer, you know – speaking of the Second Foundation, don't I? no wonder you look astonished.† Pelorat – leaned his head back as though he were going to break into loud laughter but he merely smiled. â€Å"Nothing so silly and unimportant, I assure you.† Trevize said, â€Å"If you are not speaking of the Second Foundation, Professor, what are you speaking of?† Pelorat was suddenly grave, even apologetic. â€Å"Ah, then the Mayor has not told you? – It is odd, you know. I've spent decades resenting the government and its inability to understand what I'm doing, and now Mayor Branno is being remarkably generous.† â€Å"Yes,† said Trevize, not trying to conceal an intonation of irony, â€Å"she is a woman of remarkable hidden philanthropy, but she has not told me what this is all about.† â€Å"You are not aware of my research, then?† â€Å"No. I'm sorry.† â€Å"No need to excuse yourself. Perfectly all right. I have not exactly made a splash. Then let me tell you. You and I are going to search for – and find, for I have an excellent possibility in mind – Earth.† Trevize did not sleep well that night. Over and over, he thrashed about the prison that the old woman had built around him. Nowhere could he find a way out. He was being driven into exile and he could do nothing about it. She had been calmly inexorable and did not even take the trouble to mask the unconstitutionality of it all. He had relied on his rights as a Councilman and as a citizen of the Federation, and she hadn't even paid them lip service. And now this Pelorat, this odd academic who seemed to be located in the world without being part of it, told him that the fearsome old woman had been making arrangements for this for weeks. He felt like the â€Å"boy† that she had called him. He was to be exiled with a historian who kept â€Å"dear fellowing† him and who seemed to be in a noiseless fit of joy over beginning a Galactic search for – Earth? What in the name of the Mule's grandmother was Earth? He had asked. Of course! He had asked upon the moment of its mention. He had said, â€Å"Pardon me, Professor. I am ignorant of your specialty and I trust you won't be annoyed if I ask for an explanation in simple terms. What is Earth?† Pelorat stared at him gravely while twenty seconds moved slowly past. He said, â€Å"It is a planet. The original planet. The one on which human beings first appeared, my dear fellow.† Trevize stared. â€Å"First appeared? From where?† â€Å"From nowhere. It's the planet on which humanity developed through evolutionary processes from lower animals.† Trevize thought about it, then shook his head. â€Å"I don't know what you mean.† An annoyed expression crossed Pelorat's face briefly. He cleared his throat and said, â€Å"There was a time when Terminus had no human beings upon it. It was settled by human beings from other worlds. You know that, I suppose?† â€Å"Yes, of course,† said Trevize impatiently. He was irritated at the other's sudden assumption of pedagogy. â€Å"Very well. This is true of all the other worlds. Anacreon, Santanni, Kalgan – all of them. They were all, at some time in the past, founded. People arrived there from other worlds. It's true even of Trantor. It may have been a great metropolis for twenty thousand years, but before that it wasn't.† â€Å"Why, what was it before that?† â€Å"Empty? At least of human beings.† â€Å"That's hard to believe.† â€Å"It's true. The old records show it.† â€Å"Where did the people come from who first settled Trantor?† â€Å"No one is certain. There are hundreds of planets which claim to have been populated in the dim mists of antiquity and whose people present fanciful tales about the nature of the first arrival of humanity. Historians tend to dismiss such things and to brood over the ‘Origin Question.'† â€Å"What is that? I've never heard of it.† â€Å"That doesn't surprise me. It's not a popular historical problem now, I admit, but there was a time during the decay of the Empire when it roused a certain interest among intellectuals. Salvor Hardin mentions it briefly in his memoirs. It's the question of the identity and location of the one Planet from which it all started. If ,we look backward in time, humanity flows inward from the most recently established worlds to older ones, to still older ones, until all concentrates on one – the original.† Trevize thought at once of the obvious flaw in the argument. â€Å"Might there not have been a large number of originals?† â€Å"Of course not. All human beings all over the Galaxy are of a single species. A single species cannot originate on more than one planet. Quite impossible.† â€Å"How do you know?† â€Å"In the first place.† Pelorat ticked off the first finger of his left hand with the first finger of his right, and then seemed to think better of what would undoubtedly have been a long and intricate exposition. He put both hands at his side and said with great earnestness, â€Å"My dear fellow, I give you my word of honor.† Trevize bowed formally and said, â€Å"I would not dream of doubting it, Professor Pelorat. Let us say, then, that there is one planet of origin, but might there not be hundreds who lay claim to the honor?† â€Å"There not only might be, there are. Yet every claim is without merit. Not one of those hundreds that aspire to the credit of priority shows any trace of a prehyperspatial society, let alone any trace of human evolution from prehuman organisms.† â€Å"Then are you saying that there is a planet of origin, but that, for some reason, it is not making the claim?† â€Å"You have hit it precisely.† â€Å"And you are going to search for it?† â€Å"We are. That is our mission. Mayor Branno has arranged it all. You will pilot our ship to Trantor.† â€Å"To Trantor? It's not the planet of origin. You said that much a while ago.† â€Å"Of course Trantor isn't. Earth is.† â€Å"Then why aren't you telling me to pilot the ship to Earth?† â€Å"I am not making myself clear. Earth is a legendary name. It is enshrined in ancient myths. It has no meaning we can be certain of, but it is convenient to use the word as a one-syllable synonym for ‘the planet of origin of the human species.' just which planet in real space is the one we are defining as ‘Earth' is not known.† â€Å"Will they know on Trantor?† â€Å"I hope to find information there, certainly. Trantor possesses the Galactic Library, the greatest in the system.† â€Å"Surely that Library has been searched by those people you said were interested in the ‘Origin Question' in the time of the First Empire.† Pelorat nodded thoughtfully, â€Å"Yes, but perhaps not well enough. I have learned a great deal about the ‘Origin Question' that perhaps the Imperials of five centuries back did not know. I might search the old records with greater understanding, you see. I have been thinking about this for a long time and I have an excellent possibility in mind.† â€Å"You have told Mayor Branno all this, I imagine, and she approves?† â€Å"Approves? My dear fellow, she was ecstatic. She told me that Trantor was surely the place to find out all I needed to know.† â€Å"No doubt,† muttered Trevize. That was part of what occupied him that night. Mayor Branno was sending him out to find out what he could about the Second Foundation. She was sending him with Pelorat so that he might mask his real aim with the pretended search for Earth – a search that could carry him anywhere in the Galaxy. It was a perfect cover, in fact, and he admired the Mayor's ingenuity. But Trantor? Where was the sense in that? Once they were on Trantor, Pelorat would find his way into the Galactic Library and would never emerge. With endless stacks of books, films, and recordings, with innumerable computerizations and symbolic representations, he would surely never want to leave. Besides that – Ebling Mis had once gone to Trantor, in the Mule's time. The story was that he had found the location of the Second Foundation there and had died before he could reveal it. But then, so had Arkady Darell, and she had succeeded in locating the Second Foundation. But the location she had found was on Terminus itself, and there the nest of Second Foundationers was wiped out. Wherever the Second Foundation was now would be elsewhere, so what more had Trantor to tell? If be were looking for the Second Foundation, it was best to go anywhere but Trantor. Besides that – What further plans Branno had, he did not know, but he was not in the mood to oblige her. Branno had been ecstatic, had she, about a trip to Trantor? Well, if Branno wanted Trantor, they were not going to Trantor! – Anywhere else. – But not Trantor! And worn out, with the night verging toward dawn, Trevize fell at last into a fitful slumber. Mayor Branno had had a good day on the one following the arrest of Trevize. She had been extolled far beyond her deserts and the incident was never mentioned. Nevertheless, she knew well that the Council would soon emerge from its paralysis and that questions would be raised. She would have to act quickly. So, putting a great many matters to one side, she pursued the matter of Trevize. At the time when Trevize and Pelorat were discussing Earth, Branno was facing Councilman Munn Li Compor in the Mayoralty Office. As he sat across the desk from her, perfectly at ease, she appraised him once again. He was smaller and slighter than Trevize and only two years older. Both were freshmen Councilmen, young and brash, and that must have been the only thing that held them together, for they were different in all other respects. Where Trevize seemed to radiate a glowering intensity, Compor shone with an almost serene self-confidence. Perhaps it was his blond hair and blue eyes, not at all common among Foundationers. They lent him an almost feminine delicacy that (Branno judged) made him less attractive to women than Trevize was. He was clearly vain of his looks, though, and made the most of them, wearing his hair rather long and making sure that it was carefully waved. He wore a faint blue shadowing under his eyebrows to accentuate the eye color. (Shadowing of various tints had become common among men these last ten years.) He was no womanizer. He lived sedately with his wife, but had not yet registered parental intent and was not known to have a clandestine second companion. That, too, was different from Trevize, who changed housemates as often as he changed the loudly colored sashes for which he was notorious. There was little about either young Councilman that Kodell's department had not uncovered, and Kodell himself sat quietly in one corner of the room, exuding a comfortable good cheer as always. Branno said, â€Å"Councilman Compor, you have done the Foundation good service, but unfortunately for yourself, it is not of the sort that can be praised in public or repaid in ordinary fashion.† Compor smiled. He had white and even teeth, and Branno idly wondered, for one flashing moment if all the inhabitants of the Sirius Sector looked like that. Compor's tale of stemming from that particular, rather peripheral, region went back to his maternal grandmother, who had also been blond-haired and blue-eyed and who had maintained that her mother was from the Sirius Sector. According to Kodell, however, there was no hard evidence in favor of that. Women being what they were, Kodell had said, she might well have claimed distant and exotic ancestry to add to her glamour and her already formidable attractiveness. â€Å"Is that how women are?† Branno had asked drily, and Kodell had smiled and muttered that he was referring to ordinary women, of course. Compor said, â€Å"It is not necessary that the people of the Foundation know of my service – only that you do.† â€Å"I know and I will not forget. What I also will not do is to let you assume that your obligations are now over. You have embarked on a complicated course and you must continue. We want more about Trevize.† â€Å"I have told you all I know concerning him.† â€Å"That may be what you would have me believe. That may even be what you truly believe yourself. Nevertheless, answer my questions. Do you know a gentleman named Janov Pelorat?† For just a moment Compor's forehead creased, then smoothed itself almost at once. He said carefully, â€Å"I might know him if I were to see him, but the name does not seem to cause any association within me.† â€Å"He is a scholar.† Compor's mouth rounded into a rather contemptuous but unsounded â€Å"Oh?† as though he were surprised that the Mayor would expect him to know scholars. Branno said, â€Å"Pelorat is an interesting person who, for reasons of his own, has the ambition of visiting Trantor. Councilman Trevize will accompany him. Now, since you have been a good friend of Trevize and . perhaps know his system of thinking, tell me. Do you think Trevize will consent to go to Trantor?† Compor said, â€Å"If you see to it that Trevize gets on the ship, and if the ship is piloted to Trantor, what can he do but go there? Surely you don't suggest he will mutiny and take over the ship.† â€Å"You don't understand. He and Pelorat will be alone on the ship and it will be Trevize at the controls.† â€Å"You are asking whether he would go voluntarily to Trantor?† â€Å"Yes, that is what I am asking.† â€Å"Madam Mayor, how can I possibly know what he will do?† â€Å"Councilman Compor, you have been close to Trevize. You know his belief in the existence of the Second Foundation. Has he never spoken to you of his theories as to where it might exist, where it might be found?† â€Å"Never, Madam Mayor.† â€Å"Do you think he will find it?† Compor chuckled. â€Å"I think the Second Foundation, whatever it was and however important it might have been, was wiped out in the time of Arkady Darell. I believe her story.† â€Å"Indeed? In that case, why did you betray your friend? If he were searching for something that does not exist, what harm could he have done by propounding his quaint theories?† Compor said, â€Å"It is not the truth alone that can harm. His theories may have been merely quaint, but they might have succeeded in unsettling the people of Terminus and, by introducing doubts and fears as to the Foundation's role in the great drama of Galactic history, have weakened its leadership of the Federation and its dreams of a Second Galactic Empire. Clearly you thought this yourself, or you would not have seized him on the floor of the Council, and you would not now be forcing him into exile without trial. Why have you done so, if I may ask, Mayor?† â€Å"Shall we say that I was cautious enough to wonder if there were some faint chance that he might be right, and that the expression of his views might be actively and directly dangerous?† Compor said nothing. Branno said, â€Å"I agree with you, but I am forced by the responsibilities of my position to consider the possibility. Let me ask you again if you have any indication as to where he might think the Second Foundation exists, and where he might go.† â€Å"I have none.† â€Å"He has never given you any hints in that direction?† â€Å"No, of course not.† â€Å"Never? Don't dismiss the thought easily. Think! Never?† â€Å"Never,† said Compor firmly. â€Å"No hints? no joking remarks? no doodles? no thoughtful abstractions at moments that achieve significance as you look back on them?† â€Å"None. I tell you, Madam Mayor, his dreams of the Second Foundation are the most nebulous starshine. You know it, and you but waste your time and your emotions in your concern over it.† â€Å"You are not by some chance suddenly changing sides again and protecting the friend you delivered into my hands?† â€Å"No,† said Compor. â€Å"I turned him over to you for what seemed to me to be good and patriotic reasons. I have no reason to regret the action, or to change my attitude.† â€Å"Then you can give me no hint as to where he might go once he has a ship at his disposal?† â€Å"As I have already said†¦Ã¢â‚¬  â€Å"And yet, Councilman,† and here the lines of the Mayor's face so folded as to make her seem wistful, â€Å"I would like to know where he goes.† â€Å"In that case, I think you ought to place a hyper-relay on his ship.† â€Å"I have thought of that, Councilman. He is, however, a suspicious man and I suspect he will find it – however cleverly it might be placed. Of course, it might be placed in such a way that he cannot remove it without crippling the ship, and he might therefore be forced to leave it in place†¦Ã¢â‚¬  â€Å"An excellent notion.† â€Å"Except that,† said Branno, â€Å"he would then be inhibited. He might not go where he would go if he felt himself free and untrammeled. The knowledge I would gain would be useless to me.† â€Å"In that case, it appears you cannot find out where he will go.† â€Å"I might, for I intend to be very primitive. A person who expects the completely sophisticated and who guards against it is quite apt never to think of the primitive. – I'm thinking of having Trevize followed.† â€Å"Followed?† â€Å"Exactly. By, another pilot in another spaceship. See how astonished you are at the thought? He would be equally astonished. He might not think of scouring space for an accompanying mass and, in any case, we will see to it that his ship is not equipped with our latest mass-detection devices.† Compor said, â€Å"Madam Mayor, I speak with all possible respect, but I must point out that you lack experience in space flight. To have one ship followed by another is never done – because it won't work. Trevize will escape with the first hyperspatial jump. Even if he doesn't know he is being followed, that first jump will be his path to freedom. If he doesn't have a hyper-relay on board ship, he can't be traced.† â€Å"I admit my lack of experience. Unlike you and Trevize, I have had no naval training. Nevertheless, I am told by my advisers – who have had such training – that if a ship is observed immediately prior to a jump, its direction, speed, and acceleration make it possible to guess what the jump might be – in a general way. Given a good computer and an excellent sense of judgment, a follower might duplicate the jump closely enough to pick up the trail at the other end – especially if the follower has a good mass-detector.† â€Å"That might happen once,† said Compor energetically, â€Å"even twice if the follower is very lucky, but that's it. You can't rely on such things.† â€Å"Perhaps we can. – Councilman Compor, you have hyper-raced in your time. You see, I know a great deal about you. You are an excellent pilot and have done amazing things when it comes to following a competitor through a jump.† Compor's eyes widened. He almost squirmed in his chair. â€Å"I was in college then. I am older now.† â€Å"Not too old. Not yet thirty-five. Consequently you are going to follow Trevize, Councilman. Where he goes, you will follow, and you will report back to me. You will leave soon after Trevize does, and he will be leaving in a few hours. If you refuse the task, Councilman, you will be imprisoned for treason. If you take the ship that we will provide for you, and if you fail to follow, you need not bother coming back. You will be shot out of space if you try.† Compor rose sharply to his feet. â€Å"! have a life to live. I have work to do. I have a wife. I cannot leave it all.† â€Å"You will have to. Those of us who choose to serve the Foundation must be prepared at ail times to serve it in a prolonged and uncomfortable fashion, if that should become necessary.† â€Å"My wife must go with me, of course.† â€Å"Do you take me for an idiot? She stays here, of course.† â€Å"As a hostage?† â€Å"If you like the word. I prefer to say that you will be taking yourself into danger and my kind heart wants her to stay here where she will not be in danger. – There is no room for discussion. You are as much under arrest as Trevize is, and I am sure you understand I must act quickly – before the euphoria enveloping Terminus wears off. I fear my star will soon be in the descendant.† Kodell said, â€Å"You were not easy on him, Madam Mayor.† The Mayor said with a sniff, â€Å"Why should I have been? He betrayed a friend.† â€Å"That was useful to us.† â€Å"Yes, as it happened. His next betrayal, however, might not be.† â€Å"Why should there be another?† â€Å"Come, Liono,† said Branno impatiently, â€Å"don't play games with me. Anyone who displays a capacity for double-dealing must forever be suspected of being capable of displaying it again.† â€Å"He may use the capability to combine with Trevize once again. Together, they may†¦Ã¢â‚¬  â€Å"You don't believe that. With all his folly and naivete, Trevize goes straight for his goal. He does not understand betrayal and he will never, under any circumstances, trust Compor a second time.† Kodell said, â€Å"Pardon me, Mayor, but let me make sure I follow your thinking. How far, then, can you trust Compor? How do you know he will follow Trevize and report honestly? Do you count on his fears for the welfare of his wife as a restraint? His longing to return to her?† â€Å"Both are factors, but I don't entirely rely on that. On Compor's ship there will be a hyper-relay. Trevize would suspect pursuit and would search for one. However Compor – being the pursuer – will, I assume, not suspect pursuit and will not search for one. – Of course, if he does, and if he finds it, then we must depend on the attractions of his wife.† Kodell laughed. â€Å"To think I once had to give you lessons. And the purpose of the pursuit?† â€Å"A double layer of protection. If Trevize is caught, it may be that Compor will carry on and give us the information that Trevize will not be able to.† â€Å"One more question. What if, by some chance, Trevize finds the Second Foundation, and we learn of it through him, or through Compor, or if we gain reason to suspect its existence – despite the deaths of both?† â€Å"I'm hoping the Second Foundation does exist, Liono,† she said. â€Å"In any case, the Seldon Plan is not going to serve us much longer. The great Hari Seldon devised it in the dying days of the Empire, when technological advance had virtually stopped. Seldon was a product of his times, too, and however brilliant this semimythical science of psychohistory must have been, it could not rise out of its roots. It surely would not allow for raid technological advance. The Foundation has been achieving that, especially in this last century. We have mass-detection devices of a kind undreamed of earlier, computers that can respond to thought, and – most of all – mental shielding. The Second Foundation cannot control us for much longer, if they can do so now. I want, in my final years in power, to be the one to start Terminus on a new path.† â€Å"And if there is, in fact, no Second Foundation?† â€Å"Then we start on a new path at once.† The troubled sleep that had finally come to Trevize did not last long. A touch on his shoulder was repeated a second time. Trevize started up, bleary and utterly failing to understand why he should be in a strange bed. â€Å"What – What – ?† Pelorat said to him apologetically, â€Å"I'm sorry, Councilman Trevize. You are my guest and I owe you rest, but the Mayor is here.† He was standing at the side of the bed in flannel pajamas and shivering slightly. Trevize's senses leaped to a weary wakefulness and he remembered. The Mayor was in Pelorat's living room, looking as composed as always. Kodell was with her, rubbing lightly at his white mustache. Trevize adjusted his sash to the proper snugness and wondered how long the two of them – Branno and Kodell – were ever apart. Trevize said mockingly, † Has the Council recovered yet? Are its members concerned over the absence of one of them?† The Mayor said, â€Å"There are signs of life, yes, but not enough to do you any good. There is no question but that I still have the power to force you to leave. You will be taken to Ultimate Spaceport†¦Ã¢â‚¬  â€Å"Not Terminus Spaceport, Madam Mayor? Am I to be deprived of a proper farewell from weeping thousands?† â€Å"I see you have recovered your penchant for teenage silliness, Councilman, and I am pleased. It stills what might otherwise be a certain rising twinge of conscience. At Ultimate Spaceport, you and Professor Pelorat will leave quietly.† â€Å"And never return?† â€Å"And perhaps never return. Of course,† and here she smiled briefly, â€Å"if you discover something of so great an importance and usefulness that even I will be glad to have you back with your information, you will return. You may even be treated with honor.† Trevize nodded casually, â€Å"That may happen.† â€Å"Almost anything may happen. – In any case, you will be comfortable. You are being assigned a recently completed pocket-cruiser, the Far Star, named for Hober Mallow's cruiser. One person can handle it, though it will hold as many as three with reasonable comfort.† Trevize was jolted out of his carefully assumed mood of light irony. â€Å"Fully armed?† â€Å"Unarmed but otherwise fully equipped. Wherever you go, you will be citizens of the Foundation and there will always be a consul to whom you can turn, so you will not require arms. You will be able to draw on funds at need. – Not unlimited funds, I might add.† â€Å"You are generous.† â€Å"I know that, Councilman. But, Councilman, understand me. You are helping Professor Pelorat search for Earth. Whatever you think you are searching for, you are searching for Earth. All whom you meet must understand that. And always remember that the Far Star is not armed.† â€Å"I am searching for Earth;† said Trevize. â€Å"I understand that perfectly.† â€Å"Then you will go now.† â€Å"Pardon me, but surely there is more to all of this than we have discussed. I have piloted ships in my time, but I have had no experience with a late-model pocket-cruiser. What if I cannot pilot it?† â€Å"I am told that the Far Star is thoroughly computerized. – And before you ask, you don't have to know how to handle a late-model ship's computer. It will itself tell you anything you need to know. Is there anything else you need?† Trevize looked down at himself ruefully. â€Å"A change of clothing.† â€Å"You will find them on board ship. Including those girdles you wear, or sashes, whichever they are called. The professor is also supplied with what he needs. Everything reasonable is already aboard, although I hasten to add that this does not include female companions.† â€Å"Too bad,† said Trevize. â€Å"It would be pleasant, but then, I have no likely candidate at the moment, as it happens. Still, I presume the Galaxy is populous and that once away from here I may do as I Please.† â€Å"With regard to companions? Suit yourself.† She rose heavily. â€Å"I will not take you to the spaceport,† she said, â€Å"but there are those who will, and you must make no effort to do anything you are not told to do. I believe they will kill you if you make an effort to escape. The fact that I will not be with them will remove any inhibition.† Trevize said, â€Å"I will make no unauthorized effort, Madam Mayor, but one thing†¦Ã¢â‚¬  â€Å"Yes?† Trevize searched his mind rapidly and finally said with a smile that he very much hoped looked unforced, â€Å"The time may come, Madam Mayor, when you will ask me for an effort. I will then do as I choose, but I will remember the past two days.† Mayor Branno sighed. â€Å"Spare me the melodrama. If the time comes, it will come, but for now – I am asking for nothing.†

Childrens literature Essay

Child development was broken down into four theories. These theories focused on intellectual and cognitive development as well as social development and moral judgment development. Theoretical models can be applied to children’s literature by different kinds of books. Children in the younger ages enjoy books like Dr. Seuss the cat in the hat or The Bernstein bears books that focus on things like right from wrong and education. Children learn from these kinds of books at a young age and the books can be related to their lives. As children get older books become more meaningful and become something they can relate to. Harry Potter and the Sorcerer’s Stone is the book I chose, because I felt like it was well known and something children could connect to and enjoy. The story of Harry Potter can be related to by many children. The trials the he faces as a boy living with his aunt and uncle in the â€Å"non-magic† world can be understood by some who have encountered the same things. He was unappreciated, bullied, made fun of, and treated unfairly just because he was unliked. On his eleventh birthday he finds out that he is actually a wizard and there is a school for kids just like him. His parents, who were killed when he was a baby, were also magic people, and he was excited to be able to learn about them. At the school, Hogwarts, he is befriended by two people who truly become his best friends and family, and he is finally happy to know there are people who care about him. I think this book can be related to Piaget’s Cognitive Theory of Development. Piaget’s cognitive theory of development was outlined into four periods of intelligent development. The sensorimotor period, the preoperational period, the period of concrete operations, and period of formal operations. The period of formal operations hits right at the age group that the Harry Potter series was intended for. This period occurs between the ages of eleven and fifteen when young people begin to use formal logic, engage in a true exchange of ideas, comprehend the viewpoints of others, and understand what it means to live in society. Most readers of this stage have entered adolescence and are ready for more mature topics. I think that this theory applies to this book as kids can relate to Harry’s life with the Dursley’s and the world he is living in. After finding out he is a wizard they can also relate to all the situations he will face while  there at Hogwarts. Children can use their imagination to take them away into their own world where they can get away from reality even for a moment. As far as the book itself goes, literary criticism is meant to interpret the meaning of literature. I believe this book is approached by formal criticism. Formal criticism focuses on the work itself rather than the literary history of the book. When I read this book I am not worried about the author and her life or anything about the literature. I am focused on the action and story itself and the suspense it brings to its readers. I found this criticism part of the paper a little more challenging, but I agree with my decision as I did not think that any of the others fit. There is much that children and even adults can learn from reading books. There are books for children ages zero to three that focus mainly on shapes, colors, animals, and numbers. There are books for younger children up until age ten that are about little girls or boys and their adventures that they go on with their imaginary friends. Books about friendship and forgiveness that teach children to be kind and considerate of others as well as unselfish and giving. Books for ages eleven to fifteen that focus on life as a teenager when your mother or father does not understand you and you are desperately trying to figure out who you are. Books that can teach compassion and loyalty to family and friends and just overall make you imagine worlds you could have never dreamed of. Finally to the ages of sixteen to nineteen when you are googling over that boy or girl you so wish would notice you or even if you are interested in the fantasy world of dragons and wizards, there is a book out there that can teach every one of us something about ourselves. Books are out there to teach us new things and take us places we never knew we could go. It is all about actually reading what the author has to say and listening. For me reading was a way of life and something that made me who I am today. I encourage reading for everyone and I hope that my son is as passionate about reading as I am. References Russell D. L. (2008) Pearson education, Ch. 2: The Study of Childhood: pg. 1 The Discover of Childhood. Russell D. L. (2008) Pearson education, Ch. 3: The Study of Literature; para. 20 Literary Criticism.

Writing Course for General Services Corporation Employees Essay

Writing Course for General Services Corporation Employees - Essay Example The paper throws light on General Services Corporation (GSC). In GSC, letters to customers, internal memos and emails are the most common types of written communication. Since GSC is a service company, it needs to constantly be in touch with its customers, and this makes external communication very important. There is also a lot of written communication that goes on between different departments. Most of this internal communication is normally in the form of e-mails and memos. Employees in the marketing department also have to do a lot of proposal writing for the purposes of getting more customers for the company. With all this writing that employees have to do every now and then, it is important to upgrade their writing skills so as to make the communication process easier and more efficient. The employees should receive training not only how to write well, but also how to write creatively. For instance, when writing internal memos and emails, most employees normally do not really k now how to bring out the point they want to make. This makes their written communication seem pointless, which can be quite frustrating for both the receiver and sender. However, some employees are quite good at communicating through whatever form of written communication they use. For instance, when one states his message right at the beginning instead of beating around the bush, then it is likely that whoever is reading the letter or memo will take whatever is in it with the seriousness it deserves.

The Classic Style in Mississippi and Innocents Abroad Essay - 1

The Classic Style in Mississippi and Innocents Abroad - Essay Example Classic style is the preferred style since it makes people earn frequently than the school style. Writers in Mississippi and innocents abroad practice the classic style in their articles. For instance, Mark Twain is one of the writers abroad that employ this type of writing. Comparably, classic style employs equity between the writer and audience. The writer is equal to the task and delivers as if he is part of theaudience. In school style, the writer and the audience are never equal (Loewe par. 4). The writer is to perform a task as a duty but not out of interest and willingness to do so. For instance, it is a rule to fill the required number of pages while writing in school type. Classic style therefore enables the writer to take part in facilitating a character trait in a piece of work. Mark Twain in his book describes himself from page to page and the readers fill like taking part in his life. The readers are able to share the understanding that the writer has over an article for the sole purpose of lucidity, confidence, and wish. It is also clear that use of classic style involves more fun since it is done out interest but not writing to fulfill a task given. Mark Twain shares his views of Mississipiriver in a hilarious way that one cannot imagine to hate the book ( Loewe par. 6). Effectively, the readers who pin point the weaknesses determine performance of the writer. A person writes what he can only read and avoids what he cannot read and understand to enhance his clarity and relevance. There is nothing regrettable that is, not a magic bullet in classic writing. A person is able to revise his work and identifies the mistakes, he also finds out the topic discussed to maintain the relevance of the article. Loewe (par. 5) opines that classic writing does not subject the writers to skim over the topic simply because of clarity but warrants a chance to observe effective communication skills to deliver to different audience. The writer becomes the primary sou rce of information hence trust and reliability remains the main pillars of a credible writer.In conclusion, it is therefore clear that people living along Mississippi river and abroad use classic style to write their articles.

POST TRAUMATIC STRESS AFTER TRAUMATIC INJURY Essay

POST TRAUMATIC STRESS AFTER TRAUMATIC INJURY - Essay Example This article aimed at investigating the history and tendency of PTSD after traumatic injury. The research stated null hypothesis as: Ho= â€Å"patients who develop PTSD after traumatic  brain injury would suffer the symptoms of trauma† where as the alternative hypothesis stated: Ha= â€Å"patients who develop PTSD after traumatic brain injury would not suffer from the symptoms of trauma†. Traumatic injury is taken as independent variable whereas post traumatic disorder is studied as dependent variable. Sampling procedure employed to gather data is probability sampling in which structured interview of the patients suffering form traumatic disorder were conducted. A sample of 96  patients was included in the study. The mean value  for posttraumatic amnesia was 36.97 days (SD=30.65) as established by use of â€Å"Westmead Posttraumatic Amnesia Scale†. The mean â€Å"Glasgow Coma Scale (GCS)†Ã‚  score  was 8.00 (SD=3.78). Mean posttraumatic amnesia and GCS  scores indicated that the average level of traumatic brain injury  was very severe. The 96 patients who participated in the 6-month assessment had (mean=8.00,  SD=3.78) (t=2.96, df=124, p

Article review on a Revised British COnstitution Essay

Article review on a Revised British COnstitution - Essay Example cular importance because Blair’s proposal were seen as highly significant as the Britain is a unitary state with all centralized power vested on the central government not having much transparency in its working processes. The article primarily discusses seven major constitutional proposals of the Blair government which it intended to reform and implement. They are devolution of Scotland and Wales; election of Mayor of London and major urban areas; removal of voting rights of hereditary peers in the House of Lords; incorporation of European human rights into British laws; freedom of information acts; electoral reforms at various level of government and referendum on changing the electoral system for member of parliament; and legislation for separate Supreme Court as independent judicial authority and stable government in northern Ireland. The Blair government was able to make significant inroad into the major constitutional reform proposals and help form stable governments in Scotland and wale after devolution. Even the problem of Northern Ireland, beset with internal violence, was relatively sorted out. Decentralization of power to local councils and mayors and right to information went a long way in creating transparency in government work. Referendums were held to encourage and promote public participation in government decision making were hailed as highly popular mechanism. The one area that became controversial was the reforms in the electoral system whereby though ‘single member district system would be retained but instead of casting a vote for one person only, electorate would rank candidates in order of preference, thus assuring majority rather than a plurality of vote for the winner’. The reform came under a lot of flak from major political parties because the constitutional reform had undermined their political supremacy over the smaller political parties with regional interests. Even the labor party members had shown their resentment against

Anton Chekovs A Marriage Proposal Essay Example | Topics and Well Written Essays - 750 words

Anton Chekovs A Marriage Proposal - Essay Example His fundamental focus is on the common man, their lives and problems and the manner in which they deal with them. A similar situation is also observed in the play â€Å"A Marriage Proposal†. As the name suggests the play is about Ivan Vassiliyitch or Lemov proposing Stepan Stepanovitch’s or Tschub’s daughter Natalia Stepnaovna. Although the play is extremely hilarious and chaotic yet it is observed that Chekov uses the comical aspect of the play to reveal varied human behaviors. Moreover this revelation of characters is reiterated by employing two techniques i.e. the character’s self-revelation and the explication of the fellow characters. Hence by using this technique Chekov presents the readers with an in-depth character analysis where the reader is enlightened about an individual’s personal perspective as well as the manner in which the other people perceive him. Since the commencement of the play Chekov divides the responsibility of each character’s introduction amongst the fellow characters as it is also apparent from the fact that rather than using stage directions or any other technique he utilizes dialogues as a mode for explaining the characters of Lemov and Natalia. Lemov represents a young nervous man who is at a point in life where he badly desires to get settled though he is agitated at broaching the subject with the respective bride’s father Tschub. This hesitation is highly apparent in the lines where he says, â€Å"It is not the first time I have had the honor of turning to you for assistance†¦ I beg your pardon I am a bit excited I’ll take a drink of water first† (Chekov 499). These lines depict his restlessness as well as provide the readers with an interesting insight about his character that he is a young man at brink of committing himself in a matrimonial relationship and the whole process of asking for Tschub’s daughter’s hand makes him jittery. Lemov’s dialogues also enlighten the readers about the reasons for marrying Natalia as he says, â€Å"I’m cold†¦the chief thing is to settle matters†¦I’m thirty-five a critical age you might say†¦I must live a well regulated life† (Chekov 500). In other words Lemov represents a guy in the prime age of getting married, who has a bad case of nerves about committing himself in a binding relationship. However he is brave enough to be willing to take the plunge because of his stature in life and the requirement of his health i.e. he believes having a wife will cure him from a bad heart. Moreover he is a man who has the habit of either talking in riddles or straying from the actual topic as it is evident from his failed attempts of proposing to Natalia. As time and again he says, â€Å"Only listen until I have finished†¦Ã¢â‚¬  (Chekov 502) rather than coming directly to the point he keeps getting in arguments with Natalia because of his lack of being able to steer the conversation in the right direction. Moreover through his assertions the readers realize that he considers himself a self-righteous and a fair man which is again concluded from his assertion, â€Å"my lady I have never appropriated other people’s property and I shall permit no one to accuse me of such a thing† (Chekov 503). His indignation further highlights his personality traits to the readers although Natalia believes otherwise. However it cannot be denied that he is a highly principled individual yet he has a kind heart and has the tendency of eventually giving in to an argument. This is apparent from the lines, â€Å"it was only principle of the thing the property isn’t worth much to me but the principle is worth a great deal† (Chekov 507). These parallels of opinions about Lemov’s character i.e. his personal opinion about himself and

Principles Of War Assignment Example | Topics and Well Written Essays - 500 words

Principles Of War - Assignment Example This made the Washington leave their advancement and come back to reinforce Knyphausen at Chadds Ford. In this respect, the Washington command was fooled making them abandon their position. The leadership of Washington made a big mistake by believing whatever statement they received. The statement made them recall their attacking troops back to east hence placing all their eggs in one basket. Therefore, Washington did not apply the principles of taking the advantage and positioning to defeat the enemy. Instead, they were deceived to advantage the enemy because they got the chance to march toward the south hence enabling them to strip the American defenses.Secondly, it is interesting how the British applied the principles that place the enemy in a position of disadvantage through the flexible application of combat power and this made them achieve what they wanted leading to their victory. For instance, the British penetrated the American center that caused panic on the two. The Britis h panicked because of the distance that separated them from the Americans. On the other hand, the Americans were defending their territory but could not do so for the long time since the British troops injured many of their men and suffered casualties. The Americans soldiers were wounded as well as their horses making them fall back to Birmingham meeting house. Because of the advantage that the British had gained against the Americans, Americans were forced to retreat and formed new lines in a half mile southeast

Virgin Mary of Guadalupe Essay Example | Topics and Well Written Essays - 1000 words

Virgin Mary of Guadalupe - Essay Example Mary was at the foot of the cross when Jesus was crucified, and from then on she has been known as the Mother of God and Mother of the Church. Mary lived for years after the crucifixion, and according to the traditions of the Church, told by the early Christians, she was instrumental in the formation of early Christianity, helping and even counseling the members. After her physical death (the Catholics believe that there is life after death), she is believed to have appeared in many instances. She is now ascribed to so many names, depending on the places where she appeared. Such places that are popular and favorite amongst the Catholic faithful are the Fatima (Our Lady of Fatima), Lourdes in France (Our Lady of Lourdes), then the recent Our Lady of Medjugourje. Our Lady of Guadalupe is also very popular in many countries. In the Philippines, the Patroness is the Virgin Mary and many replicas of Our Lady of Guadalupe are placed in churches for the faithful to venerate. She is also known as the Immaculate Conception, the image of this bears the words: "O Mary conceived without sin, pray for us who have recoursed to thee." The feast of the Immaculate Conception is on December 8. ... We see in Mary the figure of the woman from the beginning whose offspring will strike at the ancient serpent's head (Gen. 3:15). (365 Days with the Lord) But the feast of Our Lady of Guadalupe is on December 12. In 1999, Pope John Paul II, in his homily from the Solemn Mass at the Basilica of Our Lady of Guadalupe, during his third visit to the sanctuary, declared the date of December 12 as a Liturgical Holy Day for the whole continent. The apparition of Virgin Mary of Guadalupe is one popular among the faithful throughout the world, and is attributed for cures and conversions, especially among the Indians of Mexico. Throughout the world, several replicas have been made of the original image of the Virgin Mary that showed in the tilma as the visionary Juan Diego presented this to the Spanish Bishop Fray Juan de Zumrraga. The origin of the name "Guadalupe" is controversial. According to a sixteenth-century report, the Virgin identified herself as Guadalupe when she appeared to Juan Diego's uncle, Juan Bernardino. It is also suggested that "Guadalupe" is a corruption of a Nahuatl name "Coathlaxopeuh", which is translated as "Who crushes the serpent". The serpent referred to is Quetzalcoatl, one of the chief Aztec gods, whom the Virgin Mary "crushed" by inspiring the conversion of indigenous people to Catholicism. (Wikemedia). In the Immaculate Conception image, the Virgin is seen crushing the head of the serpent (Satan) and this is reflective of the Old Testament, when God sent Adam out of paradise, and made a future reference of the Virgin crushing the head of the serpent. Mara Guadalupe, or just Lupe, is a common female and male name among Mexican people or those with Mexican heritage. (Wikemedia) An account of the apparition states that on

The dividend discount models Essay Example | Topics and Well Written Essays - 750 words

The dividend discount models - Essay Example This model calculates the value of common stock as follows. V0 = At 5%, 6% and 4% successive dividend growth rates from first year to third year, and D0 given, we can estimate D1, D2, and D3; and given g we can estimate the value of stock (V0) as per the equation. The Dividend Discount Models are not very accurate mainly because of the difficulty of estimating a rate of growth of dividends, and unpredictability of stock markets, which may overbid or underbid prices of stocks. 2.2 The FCFF Model This model calculates the present value of all future free cash flows minus the market value of outstanding debt and preferred stock.Value of Operations = Value of Equity = Value of Operations - Value of Debt Value per Share = Value of Equity / Total Common Stock Outstanding 2.3 Multiples Approach Analysts many times use price multiples to value stocks. These multiples may be Price/Earning, Price/ Cash Flow, Price/Revenue, Price/ Book, Price/ Sales, Price/ Earnings Growth (PEG). ( Using Ratios and Multiples, n.d.) The most popular P/E Ratio is shown below: P/E = (Stock Price/ EPS) EPS = Earnings per share Higher P/E ratio denotes better growth prospects and vice versa. The drawback of this method is that it becomes meaningful only with context. The context may be skewed. Reported earnings may sometimes be inflated or depressed. Firms that go through turbulent business cycles require more investigation. Other shortcomings of multiples method is that comparable firms are hard to find within an industry or industries. 2.4 Yield Based Valuation Models These models include the Cash Return method (Cash Return = Free Cash Flow + Net Interest... Common Stocks represent an ownership position in a firm. This position entitles the holder to several privileges. An important part of value investing is valuation of common stock. There are several methods of common stock valuation, some of which we discuss in this paper.The Dividend Discount Models mainly predict the dividends, and net present value of a common stock. According to this method, the value of a dividend is the sum of all future dividends. Three types of discount models predict future dividends or value of a stock as outlined below. There are several methods, of common stock valuation, available to investors or analysts. Some of the methods outlined above are more popular ones. These methods present a more or less accurate estimate of the value of a common stock. Gordon Growth Model: This model works best for firms which show stable growth rates (not higher than that of the economy in the long term); which pay out large dividends; and which have a stable leverage. For other firms it is not very reliable.Variable Growth model: This model is most reliable for firms with unstable but moderating growth rates, and which pay dividends that equal FCFE or where FCFE are difficult to estimate. Advantages: 1. The sales numbers are more or less exact and not subject to manipulation or assumption. 2. Sales are not volatile as earnings may be. 3. Sales is a much more stable benchmark.

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Freedom Road Term Paper Essay Howard Fast, the author of the book Freedom Road, was born on November 11, 1914 and died at the age of 89 on March 12, 2003. Fast lived a long and adventurous life. A few of the things he did throughout his lifetime were; joining the American Communist party in 1943, serving a prison term in 1950 for refusing to cooperate with the House Committee on Un-American Activities, and his books were purged from American school libraries. On the other hand some of the positive things that happened in his life was that in 1953, he was rewarded the Stalin Peace Prize and in June of 1937 he married his first wife, Bette Cohen. In adjunction with his adventurous lifestyle, Fast spent most of his time writing. He wrote seven works of nonfiction, two autobiographies, fifty-two novels, five short stories one essay, and seven Masao Masuto Mysteries under the Penn name E.V. Cunningham. As well as writing, he created two films based off novels. (http://en.wikipedia.org/wiki/Howard_Fast) In the book Freedom Road, Howard Fast tells a fictional story based off the true events that occurred during the Constitutional Convention. The beginning of the book does not start the way most books start. This novel starts by talking about the main character, Gideon, as if we are supposed to know who he is. At first, this is confusing but after a couple of pages, you catch on and start to understand a lot easier. The first thing we are told about in the book is how all of the freed men from the small town of Charleston, had left a few weeks back to go vote. However, neither the town nor the men who left knew what voting actually was. Not knowing what voting was, made everyone who stayed in town very nervous and worried, they were not sure whether or not those men would be coming home or not. Therefore, when they men were spotted walking back into town everyone was extremely excited and could not wait to hear all about this voting thing. However, it seemed that none of the men were really talking, until one of them tells the town that they have some big news to share with everyone. Thus far, into the book, we have yet to hear from the main character, and we have actually been reading from his wives point of view. Once the returning men started talking, the book transitions from the wives point of view to Gideon’s, and that is when things start to pick up. We learn that the men’s big news is the fact that Gideon was elected to be a delegate. Because of his prowess in battle, the other ex-slaves looked to him as their leader in peacetime, but he was an uneducated man who felt himself unsuited for leadership. Yet knowing that his people wanted and needed him, he was determined to make himself fit into the pattern their hopes had cut out for him. However, none of them truly knew what a delegate was or what exactly a delegate did. The only thing they really knew was the Gideon would be receiving a letter once all the votes were counted to tell him if he had won the election. Several months go past in the book and nothing happens, no one in the town hears anything about Gideon being elected. Then one day, the postal man comes around and hands Gideon the letter that he had been waiting for. At this point in the book, we find out how afraid he is to go to Charleston because he is a â€Å"nigger.† He feels as though he is not very smart. He does not want to go â€Å"to city full of white houses†¦ full of white folks making fun†¦Ã¢â‚¬  (p. 16-17). So in order to help him overcome that fear Brother Peter tells him the people need a leader and because of how strong Gideon is physically and mentally, he was chosen to represent them. Because of Brother Peter, Gideon decides to go to Charleston. When he arrives in Charles and he realizes that, he has no money and no place to sleep, so he ends up sleeping under a hay barrel for the first night. It is the next morning when Gideon is offered a couple of cents for some physical labor, he reluctantly accepts the job realizing that he has no other option but to. Because of that money he is able to rent a room for the nights he will be at the convention, buy some food, and clothes that will look appropriate for the convention. Moreover, this is when we start getting into the convention. For the first couple of days Gideon was determined not to speak at the convention, in fear of making a fool of himself in front of all the educated white folk. Yet one day he is outraged and just cannot help himself, he gets up and speaks. Nevertheless, he was still embarrassed that he could not find the right words for what he was saying and for the fact that he sounded very uneducated compared to some of the rest. However when he was given some books that taught him how to read and speak properly, he began to speak out more and voice his opinion. To his surprise he was heard, people started to listen to what he was saying, and even siding with him. Fast explains that the Constitutional Convention worked because, though neither black nor poor whites were overly fond of each other, both realized they had a common enemy in a planter group. With the help of Gideon’s voice, and many others they fought against the planter group. The fought for a system of public schools, the abolition of imprisonment for debt, a simple and fair divorce law, a statute making it impossible for a wifes property to be sold in settlement of her husbands debts, and a measure for universal suffrage – which, came as close as man had ever come to giving women a break and land. Even though he fought for all of these things, the most important ones for Gideon were fair and equal education, and land. Throughout his time at the convention lets his wife slip away from him and stands by while a white northerner helps Gideons oldest son, Jeff, through medical school in Scotland; there was no medical school in America free enough from prejudice to accept him. Gideon loses site at what he loves the most in his life, and lets them all slip away because freedom seems more important than family. Some of the themes of this book are love and understanding, vigilance and perseverance, and hope. The reason why I say that a theme is love and understanding is because in the beginning of the book we hear about how his wife has stayed by his side through thick and thin. She waited for him though the war that he willingly signed up to go fight for. She let him go vote because she realized that even though no one knew exactly what it was, it was something of importance to her husband. In addition, though she has just gotten her husband back and did not want him to leave again; she understood that t his was something that he needed to do. She stood by his side, maybe not physically but mentally, throughout the entirety of the convention. Although this theme is not a main theme in the book, I think that it is a rather important one. The other theme I had mentioned was vigilance and perseverance. I believe these two themes are the main themes of the book, because everyone in this book is persevering in one way or another. Brother Peter insists that Gideon goes to the convention. Everyone at the convention is pushing for exactly what it is that they want written down, and his son is moving to a land unknown to him for an education that he cannot receive where he is. The last theme I had mentioned was hope. I believe that hope is the most predominant theme throughout the book, because every single person has hope. In the beginning, the town and the men who left were hoping that this voting thing was not going to get them killed. Gideon’s wife hoped that he would not leave her again, and when he did, she hoped that he would be okay and that she would get to see him again. The people of the convention all held on to the hope that what they say and what they want will be written down into a law. Then we have Gideon himself, he has hope that he will be able to read, write and give all freed slaves the right to an education. The theme of hope plays repeatedly throughout the story. All of the stories characters played a large role in the book, everyone influenced the book in one way or another, but a few of the characters that stood out to me are Brother Peter, Gideon, and Cardozo. The first character that really stands out to me is Brother Peter. I think the fact that he did not stand up and ask people to vote for him, as a delegate was a selfless act. All of the people in town look up to him and ask him for advice, they would have easily voted for him as they did Gideon, but brother Peter knew that Gideon would have more to learn from being a delegate than he would. Brother Peter also knew that Gideon would have more of a fight in him than he would. I th ink the reason why Brother Peter was so pushy about Gideon going to the convention was that he knew that Gideon would get things done. The other character that stands out to me is Gideon. Gideon starts in the beginning of the book being illiterate, but pushes though the struggle of learning how to read and write by himself. He also struggles with the fact that he is poor and does not measure up to some of the other people in the convention. Gideon fights for education and freedom so much that he lets go of everything that he truly loves. He lets his wife slip away and his son leaves. He forgets that he has people waiting for him back home. Even though I hate that he loses sight of the place he came from and his family, he over comes many struggles and fights to achieve his goals. The other character that stands out to me is Cardozo. Cardozo is the first person at the convention that comes up and talks to Gideon. I like the way Cardozo sees things differently, he is a black man that has been free all his life, got an education, socialized around white people his entire life. Therefore, when he first talks to Gideon he wants him to explain why black people should have en education. Once Gideon explains himself Cardozo understands, and helps Gideon as much as he can. He introduces him to all the right people, he supports him in the convention, and most of all he gave Gideon books that taught him how to read and write. He gave Gideon what he had come to fight for. I think it takes very kindhearted people to stand by someone who cannot even form the words to fight by themselves. Before I actually started reading this story, I thought it was going to be another extremely boring history book, however once I started I could not put it down. The way this story was written was fabulous. The way Fast incorporated Gideon’s thoughts, his writing and speaking was interesting. I loved that the real facts of what happened during that time was not just thrown in our faces, it was mixed into the fictional story that kept you interested. I think the way that we are lead through the past so effortlessly was a fascinating way to keep reader interested. I like the way Fast incorporated all the different kinds of people at the convention. In the story, the laws of freedom, education, and land would not have got through without the black folks and poor white folks being there. I think the way Fast portrayed Gideon, as a strong illiterate freedman was a great way to grab the reader’s attention and walk us through the past in a wonderful way. I think the only thing that Fast is really missing is more of Gideon speaking. Fast does an excellent narration of illiterate folks, but he does not do enough of it. Overall, this book was great, I will most likely be keeping it, and not reselling it so I can re-read it repeatedly.

Stresses for Trainee Counselling Psychologists | Review

Stresses for Trainee Counselling Psychologists | Review Title: A critical commentary on the following research paper: Kumary, A Martyn, B. (2008) Stresses reported by UK trainee counselling psychologists. Counselling Psychology Quarterly, March; 21:19-28 The prospect of entering any postgraduate training program can often be intimidating. Not only due to the academic commitment required, but because of the emotional demands and potential financial stranglehold placed on a student. These issues alone can leave trainees in both counselling and related psychological professions vulnerable to stress, which can not only damage the well-being of the student, but lower the overall quality of care experienced by patients when trainees are on placement (Cushway Tyler 1996; Kumary Baker 2008). Kumary Martyns make the simple argument, based loosely around Crushways (1992) study of UK clinical psychology trainees, that there are key aspects of training that impact on self-reported stress levels. These included poor supervision, financial costs, childcare, personal therapy and extra supervision. Some of these stressors identified cannot be thought of as essential or necessary aspects of training but this in itself is an area of key debate. (Kumary et al 2008). Other research has also highlighted the same key issues within counselling (Szymanska 2002), but has only looked at one issue in isolation and with this in mind, the present study was an investigation of UK counselling psychology trainees self-reports of their experiences of stress when training. One might go as far to question the rational of any study examining potential stress within such professions considering that having gone through an undergraduate degree already, students are already accustomed to a moderate l evel of stress and it simply goes with the territory (Cooper Quick 2003). On the other hand, such a study has never been conducted and may produce compelling results. Subjects were easy to identify and obtain although only UK counselling trainees who were studying for Part 1 of the BPS diploma were recruited. Are we to assume that this is when stress levels are at an optimal level? Questionnaires were sent out to all institutions. While the general characteristics of the sample are well represented, there was only a 41% return rate. This is good, but not outstanding in comparison to research conducted in similar domains, despite numerous follow-up e-mails and telephone calls (Robertson Sundstorm 1990). A financial incentive might have improved this return rate, but pre-paid return envelops were provided. However this data was collected in 2003, but not submitted for publication until 2007. Ethically, this delay in analysis and publication produces results that are already four years out of date in an education system that is constantly evolving (Hadley et al 1995). While such a simple methodology may initially seem sound, on closer inspection, the differences between the training programs of clinical and counselling are only glossed over and there is some evidence to suggest that the disparity between the two hinder a repetition of a seemingly straightforward approach last consulted in 1992 by Cushway. Aside from the time lapse, it is therefore important to consider the other issues surrounding the modification of a methodology previously used to investigate stress in clinical trainees. Firstly, counselling psychologist training tends to be less scientifically orientated than its clinical counterpart and most NHS posts are only open to Clinical Psychologists (Mayne, Norcross Sayette 2000). For example, it is generally accepted that counselling psychologists focus more on the therapeutic alliance with clients having to complete 450 hours of contact by the end of 3rd year training (Hadley et al 1995). While there are considerable similarities between the two disciplines, Norcorss (2000) documents many salient differences including professional activities, theoretical orientations, employment and training settings, graduate admissions and research areas. The question what are the differences in training clinical and counselling psychologists? -does not lend itself to an easy answer because psychology can be applied in so many ways. Traditionally, the main difference is in their training and perspective (Mayne et al 2000). It would appear to be an oversight on Kumary et als (2008) part to use a similar, modified methodology, previously applied to clinical trainees when the stress causing factors may be quite different. With these differences outlined in more detail, the old methodology would appear to require a more radical modification or adaptation from that used previously. Two main instruments were used to examine stress within the sample. The Counselling Psychology Trainee Stress Survey (CPTSS) and The General Health Questionnaire (GHQ12) (Wemeke, Goldberg Yalcin 2000). The CPTSS was developed from Cushways (1992) stress survey for clinical psychology trainees with four categories (academic stressors, placement stressors, organizational stressors and personal stressors). What is concerning is the lack of both research confirming the validity of the measure and the small brainstorm session using five trainees under those headings. Furthermore, from their discussion the CPTSS, constructed from 36 items, was only piloted on a further six trainees. This did lead to some changes being made with the authors settling on four descriptive categories slightly different from Cushways; academic demands, lack of support systems, placement stressors and personal and professional development. This displays neither convergent or discriminant validity. Finally, despi te other more valid forms of questionnaires available measuring stress (for example the Psychological Stress Measure (PMS), this study chose one which was quickly devised from a brief investigation and remains untested in the general population (Lemyre Tessier 2003; Trovato et al 2006). The General Health Questionnaire (GHQ12) on the other hand has been specifically validated for use in non-psychotic populations (Wemeke et al 2000). Because it is a shortened, 12-item version of the GHQ, it allows for quick completion, is likely to increase participant response, is quick to code and statistical mistakes also become less likely. For the purposes of this study, it appears to be the ideal choice and has been used to great effect in a large body of pervious work (Winefield, Goldney, Winefield, Tiggemann 1989; Vaglum Falkum 1999; Quek, Low, Razack, Loh 2001). A recent review by Jackson (2007) however, pointed out that the 28 item is usually used because the GHQ28 has been more widely used in other working populations, which allows for better comparisons, but the reliability coefficients have ranged from 0.78 to 0.95 in numerous studies and Jackson concludes (2007, p. 57) that: ‘In using this tool with postgraduate students conducting research in many areas of occupational health, the GHQ rarely fails to provide reliable and effective measures of well-being that usually correlate very highly with other measures of working environments or organizations Regardless of how carefully survey data is collected and analyzed, the value of the final result depends on the truthfulness of the respondents answers to the questions asked. Over the last twenty years, researchers have debated extensively about the truthfulness of peoples self-reports, and no clear cut conclusion has emerged (Zechmeister, Zechmesiter, Shaughnessy 2001). If someone is asked whether or not they enjoyed their bath, there is generally no need to question whether this accurately reflects their real feelings. However, in everyday life there are some situations in which researchers should have reason to be suspect. Survey research involves reactive measurement because respondents know that their responses are being recorded. Pressures may be strong for people to respond as they think they should rather than what they actually feel or believe (Zechmeister et al 2001). The term used to describe theses pressures is social desirability and in Kumary Martyns study (2008) the se issues are present in their entirety (Zechmeister et al 2001). For example, a trainee counselling psychologists attitudes towards their own stress and health levels, may be a far cry from their actual stressful behavioural responses. Both the questioners administered rely solely on self report and this gives rise to some further criticism. The approach is straightforward, but there is a trade-off between allowing for a simple analysis and the complex use of questionnaires in any survey based study. It is a fine balance that is difficult to maintain. Self-report questionnaires are all answered at different times and in different locations by each subject. As a result, the measures are vulnerable to inaccuracies caused by confounding variables. For example, a trainee filling in a stress based measure might have just had a particularly stressful day or experience that will effect their score. They could even have exams in a few weeks. Alternatively, reporting the issue of time-management and stress may be meaningless when the respondent evidently has time to sit down and take part in such a study anyway. The results from any self report also lack directness. While there is no ideal direct measure of stress, it is possible to get a better indication by measuring some of the physiological effects in the body. For example, stress might be better measured via heart rate, blood pressure, breathing rate, brain waves, muscle tension, skin conductance or temperature (Lemyre et al 2003). While more costly, such a study could be replicated using skin conductance monitors, worn by trainee counselling psychologists and correlate daily activities with any changes. This might produce results documenting what aspects of the course give rise to more stress and allow for re-development and changes to be applied where necessary. A more elementary approach might be to use an electronic pager device which asks every hour, how stressed are you now and what are your currently doing? In summary, researchers and clinicians must be careful when adapting clinical tools and methodologies to assess stress. They were designed for pathological disorders and validated using clinical populations and so the statistical distributions are not normal (Trovato et al 2006). As Lemyre et al (2003, p. 1159) state: The concept of stress refers to a set of affective, cognitive, somatic and behavioral manifestations within the range of functional integrity Despite this, thirteen items from the CPTSS were identified as being the most stressful issues in the sample population (none came from lack of support), which were split into two groups. The first included practical issues of finding time, funds and suitable placements. One item was also linked with negotiating these three key areas and could have a subsequent impact on their social life. A second group comprised of more general postgraduate issues: academic pressure and professional socialization. In order to determine a basis for the four groupings within the 37 single items of the CPTSS they were employed as four sub-scales (academic, placement, PPD and lack of support). These also gave acceptable levels of reliability. (Kumary et al 2008). The authors also found some good evidence for demographic variants in stress, with significantly higher stress ratings reported by younger participants and lower for those who were older. The GHQ12 results were in two scoring forms casesness and extend of distress with 54 participants identified as cases had significantly higher CPTSS scores than the 39 non-cases. Key findings from Kumary et al (2008, p. 24) included: The higher the stress rated for an aspect of counselling psychology training, the clearer the indicators of psychiatric distress became older participants had lower CPTSS ratings especially on placement issues men reported lower CPTSS ratings, most notably on academic items The support items attracted less attribution in comparison to academic, placement and PPD issues, despite pilot discussions (Kumary et al 2008), suggesting again that the methodology behind this study was flawed from the start. This does to some extent mirror Cushways (1992) data in that support was viewed by participants as a resource to ease training-induced stress, and participants viewed it as a resource to be used rather than a cause of stress because it was insufficiently provided. Again, with this knowledge available at the outset, why was the same methodology used? At this point, one might mention the issue of correlation and how this does not imply causation, but no profile of a stressed student was possible because most of the results were not significant. The authors admit themselves that the data collected is nothing to be proud of (2008, p. 25). It is difficult to believe that Krumary et al (2008) did not clearly see the unsophisticated and non-standardized status of the CPTSS as a serious issue before conducting such a study particularly when compared with more experimental research methods (Lemyre et al 2003). It is possible that the measures used were not sensitive enough to pick up on individual stress differences between participants. The fact remains however, that the fundamental assumptions were wrong and the question remains, do trainees in professions such as clinical and counselling psychology experience more stress than those within the normal population and if so are such emotional demands a critical part of training? Should t rainees be exposed to unacceptable stress levels and their apparent resilience used as an assessment criterion of professional suitability? (Hadley Mitchell 1995) The basis of this study is not sound enough to warrant any overall generalizations within the target population. The approach was oversimplified at the expense of generalized, poor-quality results. In this sense, the study has contributed little to our knowledge into how trainee counselling psychologists experience stress. The lack of an original approach is a reminder of how academic journals vary in the quality of the research they publish. It is nevertheless important that it was published to illustrate a methodology that clearly failed and thus prevents further repetition. This is the constant winding road of modern applied psychological research. References Cooper, L. C., Quick, C. J. (2003). The stress and loneliness of success. Counselling Psychology Quarterly, 16, 1-7 Cushway, D. (1992). Stress in clinical psychology trainees. British Journal of Clinical Psychology, 31, 169-179 Cushway, D., Tyler, P. (1996). Stress in clinical psychologists. British Journal of Clinical Psychologists, 31, 169-179 Goldberg DP, et al. (1978) Manual of the General Health Questionnaire (NFER Publishing, Windsor, England). Hadley Mitchell (1995). Counselling Research and Program Evaluation. London: Brooks/Cole Publishing Company Jackson, C. (2007). The General Health Questionnaire. Occupational Medicine, 57, 79 Kumary, A Martyn, B. (2008). Stresses reported by UK trainee counselling psychologists. Counselling Psychology Quarterly, 21,19-28 Lemyre, L., Tessier, R. (2003). Measuring psychological stress concept, model and measurement instrument in primary care research. Canadian Family Physician, 49, 1159-1160 Mayne, T. J., Norcross, J. C., Sayette, M. A. (2000). Insiders guide to graduate programs in clinical and counseling psychology (2000-2001 ed). New York: Guilford. Norcross C. J. (2000) Clinical Versus Counselling Psychology: Whats the Diff? Eye on Psi Chi, 5 (1), 20-22 Quek, F. K, Low, Y. W., Razack, H. A., Loh, S. C. (2001). Reliability and validity of the General Health Questionnaire (GHQ-12) among urological patents: A Malaysian study. Psychiatry and Clinical Neurosciences, 55 (5), 509-513 Robertson, M. T., Sundstrom, E. (1990). Questionnaire design, return rates, and response favorableness in an employee attitude questionnaire. Journal of Applied Psychology, 75 (3), 354-357 Szymanska, K. (2002). Trainee expectations in counselling psychology as compared to the reality of the training experience. Counselling Psychology Review, 17, 22-27 Trovato, M. G., Catalano, D., Martines, G. F., Spadaro, D., DI Corrado, D., Crispi, V., Garufi, G., Nuovo, S. (2006). Psychological stress measure in type 2 diabetes. European Review for Medical and Pharmacological Sciences, 10, 69-74 Vaglum, P., Falkum, E. (1999). Self-criticism, dependency and depressive symptoms in a nationwide sample of Norwegian physicians. Journal of Affective Disorders, 52 (1-3), 153-159 Wemeke, U., Goldberg, D., Yalcin, I. (2000). The stability of the factor structure of the General Health Questionaire. Psychological Medicine, 30, 823-829 Winefield, R. H., Goldney, D. R., Winefield, H. A., Tiggemann, M. (1989) The General Health Questionnaire: Reliability and Validity For Australian Youth. Australian and New Zealand Journal of Psychiatry, 23 (1), 53-58 Zechmeister, S. J., Zechmesiter, B. E., Shaughnessy, J. J. (2001). Essentials of Research Methods in Psychology, McGraw-Hill Higher Education Schizophrenia: the biological and psychological effect Schizophrenia: the biological and psychological effect The study of psychosis has been much published within the literature. Investigations into the biological, psychological and clinical aspects of the disorder have been greatly seen. An approach which views schizophrenia as a disturbance of information processing appears promising as a way of linking all of the aspects of the disorder. A review of the research in this area led to the suggestion that the basic disturbance in schizophrenia is a weakening of the influences of stored memories of regularities of previous input on current perception. It is argued that the link between information processing disturbances and biological abnormalities may be facilitated by the use of paradigms derived from animal learning theory (latent inhibition and Kamins blocking effect). In a number of animal model studies and indeed human subject studies, on an individuals pattern of performance in acute schizophrenics, the information gained is consistent with the cognitive model. The ways in which such an information-processing disturbance may lead to schizophrenic symptomatology will thus be outlined, with particular reference to the formation and maintenance of delusional beliefs. The core cognitive abnormality may result from a disturbance in any of the brain structures involved in the prediction of subsequent sensory input. The proposed circuit implicates in particular the hippocampus and related areas and is consistent with studies of brain pathology in schizophrenia. Thus, this paper will aim to provide an insight into the biological and psychological effects of schizophrenia and will give an insight into the current treatments available and their effects on the individual and their biological status. Introduction Understanding the varied presentation of the many types of psychotic disorders is still a major challenge within todays scientific capacity. The approaches utilized to clarify their complex nature of such disorders of the neurological system present an ongoing challenge, due to the complexity of the interaction between both biological entities (the brain) and the psychological effects. Thus, the aim of this paper is to review the evolution of our understanding of schizophrenia in terms of the biological and psychological effects of the disorder, based upon a review of the literature findings. Studies, which have been conducted regarding the life-long evolution of mental illnesses, especially schizophrenia, have been publicized for decades and this has managed to initiate the early standing of schizophrenia and of the nature of its chronic states. These experiences have further contributed to the views we hold today regarding the illness, leading in a third phase to the development of a biological-psychosocial model of its evolution which has proved useful for both theoretical and practical purposes. Finally, an understanding of therapeutic experiences and theoretical explorations based on the biological and psychological has helped to minimize the effects of the disease within the patient population. Biological basis of schizophrenia Across the findings within the literature, the question of whether schizophrenia is associated with structural or functional abnormalities of the nervous system, or both, appears to have become the principal focus in many of the biological studies of schizophrenia. A number of different methods of investigation of this system have been conducted including computed tomography studies, which have been able to reveal ventricular enlargement and cortical atrophy in a subgroup of schizophrenic patients. When such enlargement is found within the brain of the majority of patients in the early stages of the illness, they appear to be most severe in patients with negative symptoms and poor outcome. Quantitative neuropathological studies have tentatively demonstrated decreased volume of specific brain areas, neuronal loss, and other changes in the limbic system, basal ganglia, and frontal cortex. Dopamine (DA) remains the neurotransmitter most likely to be involved in schizophrenia, although t here is also evidence for disturbances of serotonin and norepinephrine. Post-mortem and positron emission tomographic studies suggest an increased number of D2 DA receptors in some schizophrenics. Neuroendocrine studies reinforce the role of DA in schizophrenics. Viral infections and autoimmune disturbances may be responsible for some types of schizophrenia, but there is no firm experimental evidence to support either hypothesis. The possibility that mixtures of structural abnormalities and functional changes involving DA occur in the same patients rather than independently as part of two syndromes (Type I, II) seems attractive. The symptoms of schizophrenia patients appear to be diverse, with different elements of the disease having different impacts on different individuals. Since Bleulers (1950) conception of the schizophrenias as a heterogenous disease composed of symptomaticlly different subgroups, attempts have been made to identify biological correlates of specific behavioral dysfunction. Diagnosis of the illness could be seen to have been fraught with difficulties. The initial lack of differentiation between the manic episodes of bipolar affective disorder and schizophrenia still presents as being greatly problematic within studies published within the literature, and subsequent attempts to differentiate between subgroups of schizophrenics have yielded no discrete classification system. The search for an etiology has also been bedeviled by this lack of distinct classification. Nevertheless, the publication of and the conduction of a number of biological theories have contributed to an understanding o f schizophrenia by identifying specific dysfunctional neural areas in determining biochemical changes associated with symptomatology and in formulating new etiological hypotheses. Neurological correlation between neurological studies and the effects of schizophrenia have been examined by research conducted through the use of magnetic resonance imaging, computed and positron emission tomography, and, also postmortem morphological changes (Koning et al, 2010). Studies of cognitive function in association with metabolic and cerebrovascular activity have contributed to the identification of discrete neural dysfunction. In addition, development of the dopamine theory and its relationship to positive symptoms has assisted in diagnostic differentiation, while recent studies on the modulatory role of neuropeptides on neurotransmitters have expanded the scope of the dopamine theory. Several biological theories have been proposed for an etiology of schizophrenia. (Krabbendam et al, 2004) Perinatal complications and viral infection have been suggested either in isolation or in conjunction with genetic factors. Low birth weight has also been proposed as a predisposing or associated factor in the subsequent development of schizophrenia. The viral hypothesis has received impetus from recent research into retroviruses capable of genetic transmission and causing latent disease onset. It is also recognized that factors other than biological, in particular, Psychosocial influences may play an etiological role in schizophrenia. Discussion of these factors, however, will not be discussed in great detail in this paper due to time restrictions. The difficulty of diagnosis As etiological studies rely to a large extent on accurate diagnosis, it is important initially to identify diagnostic problems because this aids an understanding between the interplay between biological and psychological effects, which can be noted in schizophrenics. It has long been recognized that the term schizophrenia incorporates a heterogeneous collection of subgroups, possibly with different etiologies, disease processes, and outcomes. The subsequent categorization of such patients into meaningful groups therefore relies upon differences in symptomatology and long term outcome, and fall broadly into three categories- paranoid versus nonparanoid, negative versus positive, and chronic versus acute (Goldstein Tsuang, 1988) The literature proposes that paranoid groups show a better premorbid adjustment, cognitive performance, and prognosis than the nonparanoid group (Kumra and Schulz, 2008), it has been suggested that this represents a measurement artifact and depends on whether absolute or relative measures of paranoia are used. Studies using absolute predominance measures to the exclusion of other symptoms reject many subjects displaying both sets of symptoms. Many nonpredominance studies show no differences between the groups of an increase in negative outcome as paranoid symptoms increase. Other researchers have proposed that schizophrenics could be categorized into two types placed into their category upon the basis of positive or negative symptom preponderence. Type I, or the positive symptom group, display some of the Schneiderian first rank symptoms of hallucinations and delusions, while Type 2, or the negative symptom group, show affective loss or extinction, speech content poverty, psychomotor deficits, and a general loss of drive or will. One of the problems with this categorization is that many schizophrenics display both sets of symptoms and that schizophrenics with primary positive symptoms often develop negative symptoms over time (Phillips and Silverstein, 2003). This would mean that studies using young subjects showing predominantly Positive symptoms may not be adequately differentiating between groups. Recent refinements of the positive/negative dichotomy have led to a redefinition of negative symptoms congruent with familial genetic factors, developmental dys- function, and the development of psychometric scales to measure relative symptomatology (Pickett-Schnenk et al, 2006). However, the influence of neuroleptic drugs on attentional and extrapyramidal functioning could also contribute to the development of differential symptoms. Furthermore, the effects of early environmental factors, such as perinatal trauma and familial environment, and of concurrent disorders, such as depression, are not adequately taken into account in such studies. Thus, this highlights the difficulties, which can be seen when trying to relate the biological and psychological effects of schizophrenia to a certain pathological aspect of brain development. Within the Diagnostic and Statistical Manual of Mental Disorders (DSM-III-R; APA, 1987) chronicity is defined as persistence of disturbance for more than two years with further residual diagnosis if subsequent symptoms are primarily negative. It is assumed to be associated with negative symptoms within Crows typography (Crow, 1980). This classification is the most common in the literature because of its basis in psychiatric diagnosis and its relationship to poor prognosis and to biological and cognitive deficits. For the purpose of biological research, the argument appears to be somewhat circular however because, for example, research attempts to find biological correlates of subgroups that are often operationally defined by their biological correlates. Moreover, there is significant overlap between the two groups in that many initially acute schizophrenics subsequently become chronic (by definition). While researchers across the literature publications acknowledge the heterogeneity of the disease, they continue to rely operationally on a dichotomous diagnosis. Multiple research strategies on the same subgroup would assist in isolating behavioural and biological attributions and in refining diagnostic criteria. Biochemical research and the impact on our understanding of the effects of schizophrenia Disruptions of neural biochemical processes have been extrapolated both from the effects of psychomimetic drugs and from the actions of symptom-reducing neuroleptic drugs. Drugs such as amphetamine and L-dopa, which cause psychotic conditions (e.g., hallucinations and paranoia), are known to involve excesses of dopamine release (Goodwin, 1972). Although different classes of neuroleptics are known to block acetylcholine, noradrenaline, or serotinin transmission, all of them block dopamine, and symptom reduction is thought to emanate from the latter (Millar et al, 2001). Within the dopamine theory two models of dysfunction have been proposed: autoreceptor excess, and postsynaptic receptor mechanism deficit. Different classes of neuroleptics vary in whether action is pre- or postsynaptic, but an inhibition of dopamine transmission is effected by all classes. Two classes of dopamine receptors have been identified-D1 and DP as previously mentioned, and it is believed that they are related to schizophrenia and neuroleptic effects. Distinctions between the two are based upon their actions on adenylate cyclase: stimulatory for Dl and distinct or inhibitory for D2 (Murray et al, 2008). Dl neurons, which project from the substantia nigra to the corpus striatum, are implicated in Parkinsons disease. Inhibition of Dl receptors is believed to be the origin of neuroleptic side effects, such as tardive dyskinesia and parkinsonianism. D2 receptors are associated with the antipsychotic effects of neuroleptic drugs and form the mesolimbic dopamine system which projects to the frontal cortex and some limbic forebrain structures (Tseng et al, 2008). The proposition that schizophrenic symptoms are caused by an excess of D2 receptors was initially difficult to substantiate due to drug effects and disease process. In most postmortem studies showing higher densities of dopamine receptors, previous antipsychotic drug use is also implicated (Seeman, 1986). However, in several studies subjects had never been treated with neuroleptics and still evinced increased dopamine receptor density (Trower et al, 2004). The role of dopamine receptor anomalies has also been studied using differential effects of classes of neuroleptics on dopamine receptors. In vivo Positron Emission Tomography (PET) research using the ligand [Cl raclopride has indicated that diverse classes of neuroleptic drugs administered in clinically effective doses block D2 dopamine receptors in the putamen. suggesting increased D2 dopamine density in schizophrenic subjects (Thompson et al, 2001). Research on the role of the atypical neuroleptic, clozapine, on dopamine receptors has however yielded inconsistent results. It is thought that the relative absence of extrapyramidal side effects with clozapine administration is due to a selective effect on D2 dopamine activity in the ventral tegmental area and nucleus accumbens but not in the substantia nigra or striatum. Haloperidol, on the other hand, reduces dopamine activity in both areas. The effects of both drug classes have been observed in rats using in vivo extracellular sing le-unit recordings (Tseng et al, 2009). However, clozapine also acts antagonistically on cholinergic, a-adrenergic, his- tamine, and serotonin receptors and, in addition, the combination of haloperidol with the a-noradrenergic antagonist, prazosin, produces similar effects to clozapine administration, namely, reduced basal dopamine release in the striatum but not in the nucleus accumbens (Thimm et al, 2010). Studies on cerebrospinal fluid (CSF) levels of prolactin following clozapine administration have also yielded inconsistent reslults. Prolactin release is inhibited by dopamine and increased by conventional neuroleptics. However, in at least one study it has been found that administration of clozapine to human schizophrenic subjects produced no significant increase in prolactin levels 11 hours after administration, despite moderate to marked therapeutic effects (Meltzer, Goode, Schyve, Young, Fang, 1979). Several recent studies have also implicated Dl receptor blocks in the therapeutic effects of clozapine. A further obstacle to the initial acceptance of the dopamine theory has been the time discrepancy between drug administration and antipsychotic symptomatic effects. PET studies have shown immediate binding to dopamine receptor sites, yet their clinical effect is often delayed for several weeks (Tarrier et al, 1999). There have been suggestions that receptors blocks produce an initial overactivity of dopamine release to compensate for inhibition. Further evidence for the dopamine theory has come from measurements of CSF, and plasma levels of the dopamine metabolite, homovanillic acid (HVA). Although findings in unmedicated patients have not yielded consistent differences in HVA levels between schizophrenics and controls, neuroleptic treatment increases HVA levels (Abubaker et al, 2008). In unmedicated patients, a correlation between low HVA levels and cortical atrophy and ventricular enlargement has been found in at least one study. This has led to the suggestion that dopamine excess is related to Type 1 schizophrenia, an interpretation which is supported by a good response to neuroleptic drugs in this group (Crow, 1985). In addition, Allen et al (2008) has suggested a possible deficiency of dopamine in Type 2 schizophrenics. However, the Type l-Type 2 typography has not been fully supported, and there is evidence that neuroleptic drugs elicit response in negative symptom sufferers (Allen et al, 2008). From the evidence there is little doubt of the biological role of dopamine within some forms of schizophrenia. The influence of serotonin in schizophrenia was suggested by the antagonistic activity of the psychomimetic drug, D-lysergic acid diethylamide (LSD), on serotonin transmission (Addinton and Addington, 1993). This has been studied in CSF by measuring levels of the serotonin precuresor, tryptophan, and the metabolite 5- hydroxyindole acetic acid (5-HIAA). At least one study has found reduced levels of 5-HIAA in schizophrenics and no difference between those on and off neuroleptics, but the latter group had only been drug free for a short time (three weeks). Therefore residual effects cannot be discounted. It was not stated whether subjects were also suffering from depression, which is known to decrease serotonin levels (Akbarian and Huang, 2009). Neither increasing nor decreasing serotonin levels have had a beneficial effect on schizophrenic symptoms (Akbarian and Huang, 2009). Monoamine oxidase (MAO) metabolizes dopamine, serotonin, and noradrenaline, as well as endogenous stimulants or hallucinogens such as phenylethylamine and diethltryptamine. It has therefore been hypothesized that decreased MAO activity could be contributory to schizophrenia. Studies have been conducted into platelet MAO activity in schizophrenics with varying results. Meltzer and Arora (1980) found that decreased MAO platelet activity was positively correlated with paraniod and positive symptoms. Other studies have found no un- usual MAO platelet activity in paranoid or hallucinating schizophrenics (Arts et al, 2008) Recent research has also considered the role of neuro-peptides in modulating CNS functions and the possible implications for schizophrenic symptomatology. Endorphins have been the subject of the most intensive study because of their association to proposed neural deficit areas both in biochemical and neuropathlogical research. The B, y, and (Y endorphins originate in the basal hypothalamus and modulate neurotransmitter activity in several structures of the limbic system and brain stem. Of all the biochemical theories of schizophrenia, the dopamine hypothesis has been the most consistently substantiated in research. The implication of other neurotransmitters, however, suggests a possible diffuse dysfunction with dopamine eliciting the most severe disruption. Efforts have been made to control for medication, but residual drug effects cannot be discounted. Many studies now use chlorpromazine equivalents to control for the effects of varying medication levels. The problem with this method is that, although different classes of neuroleptics all reduce dopamine levels either pre- or postsynaptically, they do not have equivalent effects on serotonin, MAO, or noradrenalin. Further problems are encountered when attempts are made to ascribe an etiological function to neurotransmitter activity. It is equally probable that any such changes are caused by the disease process rather than their being causal. Structual brain abnormalities The neuropathology of schizophrenia has received considerable recent interest in the light of positron emmission tomography (PET), postmortem, cognitive function and cerebral blood flow (CBF) research. While PET scans and postmortem investigation have concentrated on structural measurements, cognitive studies have provided tacit support for such structural changes. It has been hypothosized that neuropathological abnormalities identified in subgroups of schizophrenics could be in vitro developmental disorders either genetically transmitted or resulting from prenatal trauma (Ashburner et al, 2008). The most consistent findings across the publications within the literature have been differences in ventricular size, in some sections of the temporal limbic and nigrostriatal systems and basal ganglia, and in the prefrontal cortex. Measurements of ventricular size have however, shown considerable inconsistency, with some studies finding no significant difference between subjects and non-schizophrenic controls (Bles et al, 2010), and some reporting significant differences between chronic paranoid and hebephrenic subjects and normal controls (Bales et al, 2010). Evidence to date suggests that ventricular enlargement is only salient for a small subgroup of schizophrenics subject to chronicity or other, as yet unidentified, factors. Inconsistency in the results could be due to deviations in subject samples. It has been proposed that atrophy of specific neural areas could account for some schizophrenic symptoms. While some evidence has come directly from postmortem studies. Abnormalities have also been inferred from the results of PET and CAT scans and CBF measurements performed in conjunction with cognitive tasks designed to activate specific neural areas. Postmortem studies have identified significant cortical atrophy in the lateral nigro-striatal area (Birchwood et al, 2004) and in the limbic portions of the temporal lobe, specifically the amygdala, hippocampus, and parahippocampal gyrus (Birchwood et al, 2004). Psychotherapies and social treatments The psychological effects and impacts of schizophrenia must be emphasized. Due to the impact of the different, aforementioned parts of the brain and the CNS in schizophrenia, the psychological impact of the disease is obviously one, which takes great effect as previously mentioned. Psychotherapies are thought to be important within the current treatment lines in schizophrenia and although antipsychotic medications are the mainstay of treatment for schizophrenia, pharmacotherapy alone produces only limited improvement in negative symptoms, cognitive function, social functioning and quality of life. Additionally, it has been found that a great number of patients continue to suffer from persistent positive symptoms and relapses particularly when they fail to adhere to prescribed medications. This underlines the need for multi-modal care including psychosocial therapies as adjuncts to antipsychotic medications to help alleviate symptoms and to improve adherence, social functioning and qu ality of life (Patterson and Leeuwenkamp, 20008). A short review of the evidence that has accumulated on the efficacy of the major modalities of psychosocial treatment highlights that treatments involving social skills training, psychoeducation and cognitive behavioural therapies (CBTs) can all have a role in the treatment of individuals with schizophrenia. The reasoning behind the success of each treatment can give guidance into the psychological effects of the disease. For example, Psychoeducational interventions provide information about the disorder and its treatment to patients and their family members, and additionally inform the patients and family members about strategies to cope with schizophrenic illness. From the literature findings, it is evident that an extensive body of literature has accumulated regarding the efficacy of these interventions. Meta-analyses suggest that these interventions reduce high expressed emotion among relatives, and decrease relapse and rehospita lization rates (Pitschel et al, 2002; Giron et al, 2010). In general, interventions that include family members are found to have a much greater level of success (Pharaoh et al, 2006). Multi-family psychoeducation group approaches, which provide family psychoeducation and additionally offer an expanded social network, are found to reduce rates of relapse as are peer-to-peer education programs for families and patients (Chien et al, 2006). Cognitive Behavior Therapy (CBT) About a third of patients with schizophrenia continue to suffer from persistent psychotic symptoms despite adequate pharmacotherapy. Cognitive Behavior Therapy (CBT) has therefore been presented as a system of treatment which has emerged to address this need, and is based on the hypothesis that psychotic symptoms such as delusions and hallucinations stem from misinterpretations and irrational attributions caused by self-monitoring deficits. CBT seeks to help patients rationally appraise their experience of disease symptoms and how they respond to them, thereby reducing symptoms and preventing relapse (Turkington et al, 2008). Meta-analytic evaluations of this data have found CBT to be effective in ameliorating positive symptoms (Rector and Beck, 2001) although effect sizes of CBT have been noted to be inconsistent across studies and a recent meta-analysis of six blinded studies (Lynch et al, 2010) found CBT to be ineffective in reducing any symptoms of schizophrenia or in preventing relapse; the fairness of this analysis has been questioned (Kingdon et al, 2010). CBT is reported to be ineffective in targeting negative symptoms and its effects on other treatment domains are not well studied. Although CBT is recommended as a standard of care for persons with schizophrenia (NICE, 2009) the results are thought to give the best outcomes in patients who are willing to comply with treatment. Cognitive remediation A substantive proportion of schizophrenia patients have impaired cognition, particularly in the domains of psychomotor speed, attention, working memory and executive function, verbal learning and social cognition. These deficits are robust and persist during the illness, and serve as rate limiting factors for functional recovery (Tandon et al, 2009). Several cognitive remediation approaches have been developed over the past two decades which involve compensation strategies to organize information, use of environmental aids such as reminders and prompts, and a range of techniques designed to enhance executive function and social cognition (Eack et al, 2010). Earlier reviews and meta-analyses which have been presented and published within the literature findings have suggested that cognitive remediation leads to modest improvements in performance on neuropsychological tests but has limited generalization to functional outcomes (Pilling et al, 2002) One large meta-analysis published by McGurk et al, (2007), however, found that cognitive remediation was associated with significant improvements in cognitive performance and symptoms, as well as psychosocial functioning in schizophrenia. Cognitive remediation has been found to be more effective in studies that provided adjunctive psychiatric rehabilitation in addition to cognitive remediation. Thus, it appears to be the case that the durability of benefits of cognitive remediation are not yet set in stone. Social skills training (SST) Schizophrenia patients manifest deficits in social competence and these contribute to poor outcome. The goal of SST is to improve day-to-day living skills by focusing on components of social competence such as self-care, basic conversation, vocational skills, and recreation. These skills are practiced mostly in group settings using techniques based on operant and social learning theory. Historically, token economy was the first such intervention that sought to improve the social behavior of patients with psychiatric illness. While effective, the results did not generalize beyond the therapeutic setting. A recent meta-analysis of randomized controlled trials of social skills training in schizophrenia showed a large effect size for improvement in skills, a moderate effect size for performance-based social and community skills and for community functioning, and a small effect size for symptoms and relapse (Kurts and Mueser, 2008) Conclusions Thus, in conclusion, and in review of the findings published within the literature, it si clear that the impact of both biological aspects of the disease and psychological impacts are prevalent within the schizophrenic population. In summary, research on psychosocial approaches to treatment of schizophrenia has yielded incremental evidence of efficacy of CBT, SST, family psychoeducation, ACT and supported employment. Relatively few rigorously conducted trials of psychosocial interventions have been reported in the early course of schizophrenia, a phase of the illness when effective interventions may yield long-term outcome benefits . More hypothesis-driven research is needed to examine active ingredients of the therapeutic modalities that work, to identify the synergistic effects of combinations of interventions, and to use the knowledge which we have gained from the biological impact of the disease and the understandings of the neurological circuitry and its implications in schizoph renia to aid the development of new methods of reducing the effects of schizophrenia on the patient population.